Sage Bionetworks is a nonprofit research institute headquartered in Seattle, Washington. Its core mission is to advance biomedical research by promoting open science and radical collaboration, working to dismantle the data silos that have traditionally hindered progress in the field. The organization operates at the intersection of biomedical data management, artificial intelligence, and emerging technologies.
The institute's primary technical platform is Synapse, which serves as the infrastructure for its data-sharing mission. Synapse enables researchers globally to share, access, and reuse biomedical data at scale, currently managing approximately 3 petabytes of data for a community of over 7,000 monthly active users. All of the organization's software is open source.
Sage Bionetworks applies its collaborative model across several critical research areas, including Alzheimer's disease and rare disease initiatives. The institute's approach emphasizes rigorous ethical and privacy standards while embracing AI and emerging technologies as practical tools for the research communities it serves.






