Plume is a virtual clinic providing gender-affirming care to trans and gender non-conforming people across the United States. Founded in 2019 by Dr. Jerrica Kirkley and Dr. Matthew Wetschler, the company operates entirely online, offering hormone therapy, mental health services, sexual health care, and general wellness support via telehealth.
The company has served more than 35,000 trans adults since its founding. Plume's clinical team comprises over 60% trans and gender non-conforming staff members, reflecting its core focus on culturally competent care within this community.
Beyond its telehealth clinic, Plume operates Prism, a community platform exclusive to members. Prism provides support groups, educational resources on medical and legal transition matters, and networking opportunities among users navigating gender affirmation.






